Genomic Advancements Unleashed: Sysmex and Illumina Leading the Revolution


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Plasma-seqEnsei CRC RUO Kit 

 

 Plasma-seqEnsei CRC Kit, developed by Sysmex, utilizes next-generation sequencing (NGS) technology for the sensitive detection of genetic mutations associated with colorectal cancer. With a demonstrated sensitivity of 95% and specificity of 90%, this RUO kit shows promise for early detection and diagnosis of CRC.

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The Plasma-seqEnsei CRC RUO Kit: A Powerful Tool for Early Detection and Diagnosis of Colorectal Cancer


The Plasma-seqEnsei CRC RUO Kit is a plasma sequencing kit used to detect genetic mutations associated with colorectal cancer (CRC). The kit is developed by Sysmex and is available as a RUO product, which means it is intended for research and non-commercial use.

The Plasma-seqEnsei CRC kit uses next-generation sequencing (NGS) technology to sequence plasma DNA. Plasma DNA is DNA released into the blood plasma by tumor cells. The kit uses an approach called "exome capture," which specifically targets regions of the DNA that are likely to contain mutations associated with CRC.

The Plasma-seqEnsei CRC kit was evaluated in a clinical study published in 2022. The study showed that the kit had a sensitivity of 95% and a specificity of 90% for the detection of mutations associated with CRC.


Here are the key features of the Plasma-seqEnsei CRC kit:

  • Uses next-generation sequencing (NGS) technology
  • Specifically targets regions of the DNA that are likely to contain mutations associated with CRC
  • Has a sensitivity of 95% and a specificity of 90% for the detection of mutations associated with CRC

The Plasma-seqEnsei CRC kit is a powerful tool that can be used for the early detection and diagnosis of colorectal cancer. It is still under development, but it has the potential to revolutionize the management of CRC.

How the Plasma-seqEnsei CRC Kit Works

The Plasma-seqEnsei CRC kit works by first collecting a blood sample from the patient. The blood sample is then processed to isolate the plasma DNA. The plasma DNA is then subjected to exome capture, which enriches the DNA for regions that are likely to contain mutations associated with CRC. The enriched DNA is then sequenced using NGS technology.

The sequencing results are then analyzed to identify any mutations that are associated with CRC. If mutations are found, they can be used to help diagnose CRC and to guide treatment decisions.

The Benefits of the Plasma-seqEnsei CRC Kit

The Plasma-seqEnsei CRC kit offers a number of benefits over traditional methods of detecting CRC, including:

  • Early detection: The kit can be used to detect CRC at an early stage, when it is more treatable.
  • Increased accuracy: The kit has a high sensitivity and specificity, which means that it is less likely to miss or incorrectly identify CRC.
  • Reduced invasiveness: The kit only requires a blood sample, which is less invasive than other methods of detecting CRC, such as colonoscopy.


The Plasma-seqEnsei CRC kit is a promising new tool for the early detection and diagnosis of colorectal cancer. It is still under development, but it has the potential to revolutionize the management of CRC.


Sysmex and Illumina: Two Leading Companies in DNA Sequencing

Sysmex and Illumina are two of the leading companies in DNA sequencing. Both companies offer a wide range of products and services for DNA sequencing, including sequencers, consumables, and software.

Sysmex


Sysmex's DNA sequencers are used in a variety of applications, including:

  • Clinical diagnostics: DNA sequencing is used to diagnose genetic diseases, such as cancer and sickle cell anemia.
  • Research: DNA sequencing is used to study the human genome and to develop new drugs and treatments.
  • Forensics: DNA sequencing is used to identify people and to solve crimes.

Illumina


The company specializes in DNA sequencing technology.

Illumina's DNA sequencers are known for their high throughput and affordability. The company offers a variety of sequencers for different applications, including the MiSeq, HiSeq, and NovaSeq.

Illumina's DNA sequencers are used in a variety of applications, including:

  • Clinical diagnostics: DNA sequencing is used to diagnose genetic diseases, such as cancer and sickle cell anemia.
  • Research: DNA sequencing is used to study the human genome and to develop new drugs and treatments.
  • Agriculture: DNA sequencing is used to improve crop yields and to develop new crops.

Sysmex and Illumina are both excellent choices for DNA sequencing.  

Sysmex and Illumina: Revolutionizing Genomic Analysis



Introduction to Sysmex:

Sysmex Corporation, a global leader in diagnostic solutions, has been at the forefront of advancing healthcare through cutting-edge technologies. In the realm of genomics, Sysmex has played a pivotal role in developing innovative solutions that enhance our understanding of genetic information. With a commitment to precision and reliability, Sysmex offers a range of genomic tools and platforms designed to meet the diverse needs of researchers and clinicians.

Sysmex Genomic Solutions:

Sysmex's genomic solutions encompass a spectrum of technologies and instruments tailored for various applications. From DNA sequencing to molecular diagnostics, Sysmex provides state-of-the-art tools that empower researchers and healthcare professionals to unlock the secrets hidden within the genome. The company's dedication to technological excellence and scientific innovation positions Sysmex as a trusted partner in genomics research.

Illumina: Illuminating the Genomic Landscape:

Illumina, a pioneer in genomics, has revolutionized DNA sequencing with its cutting-edge technologies. The company's sequencing platforms, including the widely acclaimed MiSeq, have set new standards for accuracy, speed, and scalability. Illumina's commitment to driving genomics forward has positioned it as a key player in the genomics landscape.


Illumina Sequencing Platforms:

Illumina's sequencing platforms, renowned for their exceptional accuracy and high throughput, have become indispensable tools in genomics research. The MiSeq, HiSeq, and NovaSeq systems, among others, cater to a spectrum of research needs. Whether unraveling the intricacies of the human genome or exploring the diversity of microbial communities, Illumina's platforms provide researchers with the flexibility and reliability required for diverse genomic applications.

Collaboration for Advancing Genomics:

The collaboration between Sysmex and Illumina represents a synergy of expertise and innovation in genomics. By combining Sysmex's diagnostic proficiency with Illumina's sequencing prowess, the partnership aims to push the boundaries of genomic analysis. Researchers benefit from a comprehensive suite of tools that seamlessly integrate into their workflows, providing a holistic approach to genomics.


Applications in Research and Healthcare:

Sysmex and Illumina technologies find applications across a broad spectrum of research and healthcare domains. From advancing cancer genomics to facilitating non-invasive prenatal testing, the collaborative efforts of Sysmex and Illumina contribute to groundbreaking discoveries and improved patient care.

Technological Advancements:

Both Sysmex and Illumina continue to invest in research and development, driving technological advancements in genomics. From enhanced sequencing chemistries to streamlined bioinformatics solutions, the commitment to innovation ensures that researchers have access to state-of-the-art tools for their genomic endeavors.


In the dynamic landscape of genomics, Sysmex and Illumina stand as pillars of innovation, providing researchers and healthcare professionals with the tools needed to navigate the complexities of the genome. Through a shared commitment to advancing genomic analysis, Sysmex and Illumina contribute to the ongoing revolution in our understanding of genetic information, paving the way for a future of personalized medicine and transformative discoveries.